SANAHEAL
Introducing
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Aspiring Healthy Healing

Meet Our Team

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Hyunwoo Yuk

Graduate student at MIT Mechanical Engineering & world-renowned expert of hydrogels, soft materials and 3D printing
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Xuanhe Zhao

Professor at MIT Mechanical Engineering & world-leading expert of hydrogels and soft materials
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Christoph S. Nabzdyk

Assistant professor at Mayo Clinic & medical device expert, anesthesiologist and critical care physician

Our Technology - Reinventing Tissue Adhesives

Developed in collaboration between MIT and Mayo Clinic, our bioadhesive technologies address challenges in the existing tissue adhesives to provide the next-generation solutions for unmet clinical demands.

Technology 1: ​Hemostatic Bioadhesive Paste

Our hemostatic bioadhesive paste can provide coagulation-independent hemostatic tissue sealing within 10 seconds - offering hemostatic super glue for surgeries!

Clinical Advantages
  • Simple & preparation-free use
  • Rapid hemostatic sealing within 10 seconds
  • No blood coagulation required (applicable to anti-coagulated/coagulopathic patients)
  • Biocompatible & biodegradable
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Potential Indications
  • Intraoperative hemostatic agent for cardiovascular, hepatic, spinal, and general surgeries
  • Emergency/urgent care hemostatic agent
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Related Patents
​U.S. No. 62/942,874

Technology 2: ​Bioadhesive Patch

Our bioadhesive patch can provide suture-free fluid- and air-tight sealing of organs within 10 seconds - offering surgical duct tape for operating room!

Clinical Advantages
  • Simple & preparation-free use
  • Rapid sealing of wet tissues within 10 seconds
  • Biocompatible & biodegradable
  • Compatible with minimally-invasive surgery tools​
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Potential Indications
  • Fluid-tight sealing of cardiovascular and gastrointestinal organs in open and minimally-invasive surgeries
  • Air-tight sealing of thoracic organs in open and minimally-invasive surgeries
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Related Patents
U.S. No. 62/845,976, 63/034,644, 63/091,076, 63/091,105

More on Our Technologies & Team

Publications & Media Highlights

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Published Paper
​Yuk et al., Dry double-sided tape for adhesion of wet tissues and devices, Nature 575, 169-174 (2019) (link)

Related Technology
​Bioadhesive patch

Media Highlights
  • MIT News (link)
  • Editor's Choice, Science Translational Medicine (link)
  • Behind the paper (link)
  • BBC (link)
  • US News (link)

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Published Paper
Chen#, Yuk# et al.,  Instant tough bioadhesive with triggerable benign detachment, Proceedings of National Academy of Science 117, 15497-15503 (2020)​ (link)

Related Technology
​Bioadhesive patch

Media Highlights
  • MIT News (link)
  • Medgadget (link)
  • New Atlas (link)

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Published Paper
Deng#, Yuk# et al., Electrical bioadhesive interface for bioelectronics, Nature Materials, doi: 10.1038/s41563-020-00814-2 (2020) (link)

Related Technology
​Bioadhesive patch

Media Highlights
  • Behind the paper (link)

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Published Paper
Yuk et al., Barnacle-inspired paste for instant hemostatic tissue sealing, (Preprint) bioRxiv 2020.12.12.422505, v1, submitted: Dec 2020 (link)

Related Technology
Hemostatic bioadhesive paste

Awards & Recognitions

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 Video Highlight by MIT MechE Department

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MIT Deshpande Center grant award
​($50K, non-dilutive)

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The ZOLL Foundation award
​($40K, non-dilutive)

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2020 Collegiate Inventors Competition Graduate Winner, ​National Inventors Hall of Fame (link)
Copyright © SanaHeal 2021