SANAHEAL

Meet Our Team

Hyunwoo Yuk

Graduate student at MIT Mechanical Engineering & world-renowned expert of hydrogels, soft materials and 3D printing

Xuanhe Zhao

Professor at MIT Mechanical Engineering & world-leading expert of hydrogels and soft materials

Christoph S. Nabzdyk

Assistant professor at Mayo Clinic & medical device expert, anesthesiologist and critical care physician

Our Technology - Reinventing Tissue Adhesives

Developed in collaboration between MIT and Mayo Clinic, our bioadhesive technologies address challenges in the existing tissue adhesives to provide the next-generation solutions for unmet clinical demands.

Technology 1: Hemostatic Bioadhesive Paste

Our hemostatic bioadhesive paste can provide coagulation-independent hemostatic tissue sealing within 10 seconds - offering hemostatic super glue for surgeries!

Clinical Advantages

Simple & preparation-free use
Rapid hemostatic sealing within 10 seconds
No blood coagulation required (applicable to anti-coagulated/coagulopathic patients)
Biocompatible & biodegradable

Potential Indications

Intraoperative hemostatic agent for cardiovascular, hepatic, spinal, and general surgeries
Emergency/urgent care hemostatic agent

Related Patents
U.S. No. 62/942,874

Technology 2: Bioadhesive Patch

Our bioadhesive patch can provide suture-free fluid- and air-tight sealing of organs within 10 seconds - offering surgical duct tape for operating room!

Clinical Advantages

Simple & preparation-free use
Rapid sealing of wet tissues within 10 seconds
Biocompatible & biodegradable
Compatible with minimally-invasive surgery tools

Potential Indications

Fluid-tight sealing of cardiovascular and gastrointestinal organs in open and minimally-invasive surgeries
Air-tight sealing of thoracic organs in open and minimally-invasive surgeries

Related Patents
U.S. No. 62/845,976, 63/034,644, 63/091,076, 63/091,105

Publications & Media Highlights

Published Paper
Yuk et al., Dry double-sided tape for adhesion of wet tissues and devices, Nature 575, 169-174 (2019) (link)

Related Technology
Bioadhesive patch

Media Highlights

MIT News (link)
Editor's Choice, Science Translational Medicine (link)
Behind the paper (link)
BBC (link)
US News (link)

Published Paper
Chen#, Yuk# et al., Instant tough bioadhesive with triggerable benign detachment, Proceedings of National Academy of Science 117, 15497-15503 (2020) (link)

Related Technology
Bioadhesive patch

Media Highlights

MIT News (link)
Medgadget (link)
New Atlas (link)

Published Paper
Deng#, Yuk# et al., Electrical bioadhesive interface for bioelectronics, Nature Materials, doi: 10.1038/s41563-020-00814-2 (2020) (link)

Related Technology
Bioadhesive patch

Media Highlights

Behind the paper (link)

Published Paper
Yuk et al., Barnacle-inspired paste for instant hemostatic tissue sealing, (Preprint) bioRxiv 2020.12.12.422505, v1, submitted: Dec 2020 (link)

Related Technology
Hemostatic bioadhesive paste