SANAHEAL
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Soft Materials for Hard Problems in Healthcare

The Clinical Problem

Rapid & Effective Repair of Injured Tissues Remains Challenging in Various Clinical Scenarios
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Nature-Inspired Solutions

Learning from Nature to Achieve Rapid, Robust, Blood-Resistant Tissue Sealing Capability
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Engineered Based on Materials with History of Use in FDA-Approved Medical Devices
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In Diverse Form Factors For Various Applications & Indications*
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*Base IPs were invented at MIT & Mayo Clinic by the co-founders of SanaHeal | SanaHeal signed Option to license the base IPs from MIT & Mayo Clinic

Adhesion Performance & Biosafety

SanaHeal's Bioadhesives Achieve Superior Adhesion Performance, Biosafety & Tunable Biodegradability
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SanaHeal Bioadhesives in Action

Bioadhesive Paste for Rapid & Coagulation-Independent Control of Hemorrhage
​*Ex vivo porcine aorta | Blood pressure = 150 mmHg | Heparinized porcine blood
*In vivo anti-coagulated pig (ACT = 1,000 s) | Bleeding rate ~15 mL/min
Bioadhesive Patch for Rapid & Fluid-/Air-Tight Seal of Organ Injuries
*In vivo pig colonic injuries | Sutureless repair by the bioadhesive patch

Publications & Media Highlights

Platform Technologies & Pre-Clinical Studies Published in Prestigious Peer-reviewed Journals
Dry double-sided tape for adhesion of wet tissues and devices, Nature 575, 169-174 (2019)
​Highlighted in 
MIT News, BBC, US News, CBS Boston
Instant tough bioadhesive with triggerable benign detachment, Proceedings of National Academy of Science 117, 15497-15503 (2020)
Highlighted in 
MIT News, New Atlas, Popular Mechanics
Electrical bioadhesive interface for bioelectronics, Nature Materials 20, 229-236 (2021)
A Multifunctional origami patch for minimally invasive tissue sealing, Advanced Materials 33, 2007667 (2021)
​Highlighted in 
MIT News, Mayo Clinic Discovery's Edge
Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue, Nature Biomedical Engineering 5, 1131-1142 (2021)
​Highlighted in 
MIT News, US News, WIRED, World Economic Forum
​An off-the-shelf bioadhesive patch for sutureless repair of gastrointestinal defects, Science Translational Medicine 14, eabh2857 (2022)
​Highlighted in 
MIT News, New Scientist

 A strain-programmed patch for the healing of diabetic wounds, Nature Biomedical Engineering 6​, 1118-1133 (2022)​
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